Doctors Ready War on Farm Antibiotics

California Farmer
July 6, 2001

The San Francisco Medical Society (SFMS) that launched the war on farm use of antibiotics, recently won the support of the powerful American Medical Association (AMA), which pretty much adopted the same resolution seeking limits on farm antibiotic use. Last week SFMS conducted an Antibiotics and Agriculture Leadership Forum in San Francisco, but invited agricultural and veterinarian leaders, for the most part, stayed home.

The California resolution adopted by the AMA House of Delegates said in part, "The spread of bacterial resistance arises not only from unnecessary clinical use in human medication, but also from massive use in animal agriculture, with increasing evidence that resistance developed in animals is spreading to human pathogens." It said the California Medical Association was beginning to address the unnecessary clinical use problem.

The AMA resolution brought an immediate response from Washington D.C. based Animal Health Institute (AHI), which represents Pharmaceutical interests. "While we recognize the importance of antibiotics in human health, the AMA resolution is far too broad and sweeping, confuses therapeutic and subtherapeutic uses and is an ineffective solution to addressing antibiotic resistance."

Despite invitations to California veterinary and other agriculturists, the defense of farm use of antibiotics was left to Randy Singer, an epidemiologist at the University of Illinois College of Veterinary Medicine, who was outgunned by seven experts and activists on other side.

Singer attempted to strike a balance between needed use, overuse, ease of feed store availability and too few veterinarians for proper oversight. He was also critical of the feed/farm press that only tells farmers what they want to hear.

"There is definitely abuse of antibiotics in the livestock," Singer asserted, "but the question is how do you balance the need for animal health with the problem of persistence of antibiotics in the environment, and the increases of resistance to antibiotics.

"Antibiotics used to improve animal growth and feed efficiency can reduce subclinical disease and improve productive performance and overall health," he said.

Everyone seemed to agree that there is a lack of accurate data. AHI states that, "about 20 million pounds (of antibiotics) are used in animals, only 2.7 million pounds (13%) are used for growth promotion." Margaret Mellon, Union of Concerned Scientists, called this estimate a "repeated myth." She added that research sponsored by her organization from public sources shows that animal agriculture uses more than 50 million pounds of antibiotics a year, with more than 25 million pounds a year just to promote growth in animals for "non-therapeutic" purposes.

Mellon admitted that no one knows for sure the amount of antibiotics used for human health, but that their study suggests 3-million pounds. "Our estimate suggest eight time more antibiotics are used for nontherapetutic purposes in the three major livestock sectors than in human medicine. Our report has been out for six months and the numbers have gone unchallenged. The government needs to collect data from users and pharmaceutical companies."

Antibiotic use in agriculture "increases the risk of antibiotic-resistant foodborne illnesses and increases the risk of treatment failure or worse diseases," says Tamar Barlam, a doctor with the Center for Science in the Public Interest, Harvard Medical School. She noted that Quinolene-resistant Campylobacter in Minnesota poultry increased from 1.3% in 1992 to 10.2% in 1998

In October 2000 the FDA's Center for Veterinary Medicine proposed to withdraw fluoroquinolines for animal use. While one maker agreed, Bayer Corporation has chosen to fight the proposed ban.

While the Forum's organizer Steve Heilig, SFMS's director of public health and education and Litjen J. Tan, a senior scientist with AMA, seemed to hold out for compromise with agriculture, the Bayer decision is the trust dividing line between the two sides.

"California's Foster Farms and Zacky were ready to voluntarily pull fluoroquinolines from use, but backed off after the decision," explained Singer. "I don't think it was about money, it was about banning a product based only on a perceived risk that could turn into long term policy."

The question left hanging was whether trust could be rebuilt and compromise based on voluntary stewardship reached, or if war in the media, courts and legislative halls is the choice of both sides over solutions. While the compromise door was left open, meetings co-chair Lester Breslow, dean emeritus of UCLA's School of Public Health said, "It is like what we faced with tobacco, we need to identify the enemy – who's standing in the way?"

That sounds more like a challenge to fight than find solutions.


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